Pediatric Acute Myeloid Leukemia: Unraveling Complexities in Intensive Chemotherapy and the Emergence of Superbugs – A Case Study

This case report offers new insights into the complexities of pediatric AML management, with a focus on the emergence of CRPA. The discovery of a high-risk CRPA clone with detailed genomic data underscores the growing challenge of antimicrobial resistance in pediatric oncology. The persistent presence of CRPA and ongoing bone marrow failure highlight the difficulties in managing these complications. This case calls for a reassessment of treatment strategies and encourages further research to improve outcomes in pediatric AML, emphasizing the need for a multidisciplinary approach to address infectious complications and antimicrobial resistance.

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Publication Details

Journal
Infection and Drug Resistance
Published
2024-10-01
DOI
https://doi.org/10.2147/idr.s478065
Citations
1
Primary Topic
Acute Myeloid Leukemia Research
Type
article
Field-Weighted Citation Impact
0.45
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article

Pediatric Acute Myeloid Leukemia: Unraveling Complexities in Intensive Chemotherapy and the Emergence of Superbugs – A Case Study

Sandip Patil, Xue Tang, Xinye Li, Sixi Liu et al.
1 citations
Infection and Drug Resistance
Acute Myeloid Leukemia Research
0.45
article

Pediatric Acute Myeloid Leukemia: Unraveling Complexities in Intensive Chemotherapy and the Emergence of Superbugs – A Case Study

Sandip Patil, Xue Tang, Xinye Li, Sixi Liu, Huirong Mai, Ying Wang, Feiqiu Wen
article en
1 citations

Abstract

This case report offers new insights into the complexities of pediatric AML management, with a focus on the emergence of CRPA. The discovery of a high-risk CRPA clone with detailed genomic data underscores the growing challenge of antimicrobial resistance in pediatric oncology. The persistent presence of CRPA and ongoing bone marrow failure highlight the difficulties in managing these complications. This case calls for a reassessment of treatment strategies and encourages further research to improve outcomes in pediatric AML, emphasizing the need for a multidisciplinary approach to address infectious complications and antimicrobial resistance.

Infection and Drug ResistanceVol. Volume 17
Shenzhen Children's Hospital (CN)
Zero hunger
Openalex Percentile: Top 32%
Acute Myeloid Leukemia Research
0.45
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