Downregulation of Circular RNA Gla Reduced Astrocyte Inflammatory Status by Regulating miR-488/MEKK1 Levels and Promoted Functional Recovery After Spinal Cord Injury
Following SCI, downregulation of circGla expression in astrocytes can reduce inflammatory manifestations and stimulate long-term functional recovery in mice through miR-488 and MEKK1.
Authors
- Wei Jiang (ORCID: https://orcid.org/0000-0003-4414-595X)
- Yuepeng Fang
- Bin Ning (ORCID: https://orcid.org/0000-0002-7592-9485)
- Qiang Shao (ORCID: https://orcid.org/0000-0001-7109-6845)
- Ce Zhang (ORCID: https://orcid.org/0000-0003-0574-8141)
- Ying Zhang (ORCID: https://orcid.org/0000-0002-1116-2182)
- Zhiyuan Zhang (ORCID: https://orcid.org/0000-0001-9067-0670)
- Qingfa Chen (ORCID: https://orcid.org/0000-0002-3502-0234)
- yongcheng Yin (ORCID: https://orcid.org/0009-0001-5434-1869)
Institutions
- Weifang Medical University (CN)
- Shandong University (CN)
- Jinan Central Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2024-10-01
- DOI
- https://doi.org/10.2147/jir.s467940
- Citations
- 5
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.17