Performance evaluation of an inorganic optical fibre dosimeter for use in external beam radiotherapy with pulsed beams

<i>Objective</i>. Optical fibre dosimeters (OFDs) offer great promise for real-time<i>in vivo</i>dose measurement in radiation-based treatment modalities such as radiotherapy and brachytherapy. This is attributed to their many useful qualities such as high spatial resolution and sensitivity. However, there are several requirements that an optical fibre dosimeter must meet to be acceptable for dose measurement in a specified treatment modality. In this work, the dosimetric performance of a novel optical fibre dosimeter for use in external beam radiotherapy is presented.<i>Approach</i>. The dosimeter was characterised for photon beam energies between 6-15 MV using a Varian TrueBeam Linac at dose rates between 100-2400 MU/min and assessed based on its repeatability, dose dependence, dose rate dependence, energy dependence and dose-per-pulse dependence.<i>Main Results</i>. The results demonstrated excellent short-term repeatability of 0.3%, good linearity in response (R2>0.9997), and minor dose rate dependence between 0.53%-2.49% for all beam qualities investigated. As the scintillator of the OFD is non-water equivalent, Monte-Carlo-TOPAS simulations were used to calculate the absorbed dose energy dependence. A dose-per-pulse dependence was also investigated and compared with dosimetry measurements made with an ionisation chamber and simulated from the treatment planning system. An over-response of 20%was found at the lowest investigated dose-per-pulse, and an under-response of 34%was found at the highest investigated dose-per-pulse. This is believed to be due to an intrinsic energy dependence making this type of OFD unsuitable for external beam radiotherapy dosimetry.<i>Significance</i>. The OFD evaluated in this work was primarily designed for high-dose-rate brachytherapy whereas this study includes the first measurements made in external beam radiotherapy and highlights the challenges of transferability of the dosimeter to a different radiation source.

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Journal
Physics in Medicine and Biology
Published
2024-10-08
DOI
https://doi.org/10.1088/1361-6560/ad84b7
Primary Topic
Advanced Radiotherapy Techniques
Type
article
Field-Weighted Citation Impact
0.00

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Performance evaluation of an inorganic optical fibre dosimeter for use in external beam radiotherapy with pulsed beams

Alan R. Hounsell, Owen McLaughlin, Carla McDonnell, Conor K. McGarry et al.
Physics in Medicine and Biology
Advanced Radiotherapy Techniques
article

Performance evaluation of an inorganic optical fibre dosimeter for use in external beam radiotherapy with pulsed beams

Alan R. Hounsell, Owen McLaughlin, Carla McDonnell, Conor K. McGarry, Elfed Lewis, Sinéad O’Keeffe, Kevin M. Prise
article en

Abstract

<i>Objective</i>. Optical fibre dosimeters (OFDs) offer great promise for real-time<i>in vivo</i>dose measurement in radiation-based treatment modalities such as radiotherapy and brachytherapy. This is attributed to their many useful qualities such as high spatial resolution and sensitivity. However, there are several requirements that an optical fibre dosimeter must meet to be acceptable for dose measurement in a specified treatment modality. In this work, the dosimetric performance of a novel optical fibre dosimeter for use in external beam radiotherapy is presented.<i>Approach</i>. The dosimeter was characterised for photon beam energies between 6-15 MV using a Varian TrueBeam Linac at dose rates between 100-2400 MU/min and assessed based on its repeatability, dose dependence, dose rate dependence, energy dependence and dose-per-pulse dependence.<i>Main Results</i>. The results demonstrated excellent short-term repeatability of 0.3%, good linearity in response (R2>0.9997), and minor dose rate dependence between 0.53%-2.49% for all beam qualities investigated. As the scintillator of the OFD is non-water equivalent, Monte-Carlo-TOPAS simulations were used to calculate the absorbed dose energy dependence. A dose-per-pulse dependence was also investigated and compared with dosimetry measurements made with an ionisation chamber and simulated from the treatment planning system. An over-response of 20%was found at the lowest investigated dose-per-pulse, and an under-response of 34%was found at the highest investigated dose-per-pulse. This is believed to be due to an intrinsic energy dependence making this type of OFD unsuitable for external beam radiotherapy dosimetry.<i>Significance</i>. The OFD evaluated in this work was primarily designed for high-dose-rate brachytherapy whereas this study includes the first measurements made in external beam radiotherapy and highlights the challenges of transferability of the dosimeter to a different radiation source.

Physics in Medicine and BiologyVol. 69(21)
Queen's University Belfast (GB), Belfast Health and Social Care Trust (GB), University of Limerick (IE), The Northern Ireland Cancer Centre (GB)
European Commission, Horizon 2020 Framework Programme
Affordable and clean energy
Openalex Percentile: Top 75%
Advanced Radiotherapy Techniques
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