Contribution of the Activated mTOR-STAT3 Pathway to the Pathogenesis of Focal Cortical Dysplasia Type IIIa in Pediatric Patients through Astrocyte Proliferation Mediation
The mTOR-STAT3 pathway was demonstrated to be substantially associated with FCD IIIa in pediatric patients. The activation of the mTOR-STAT3 signaling pathway may contribute to the pathogenesis of FCD IIIa in pediatric patients by modulating the proliferation of astrocytes.
Authors
- Jiangya Wang
- Xinying Zhang (ORCID: https://orcid.org/0000-0001-7668-8110)
- Kang Lin (ORCID: https://orcid.org/0009-0009-6716-9226)
- Jiang Wu (ORCID: https://orcid.org/0000-0001-6711-6938)
- Yuanyuan Lv (ORCID: https://orcid.org/0000-0003-4736-3733)
- Yang Li (ORCID: https://orcid.org/0009-0004-3740-097X)
Institutions
- Hebei Medical University (CN)
- Fourth Hospital of Hebei Medical University (CN)
- Hebei General Hospital (CN)
- Baoding People's Hospital (CN)
Publication Details
- Journal
- Current Molecular Medicine
- Published
- 2024-10-08
- DOI
- https://doi.org/10.2174/0115665240301053240919071840
- Citations
- 1
- Primary Topic
- Cerebral Venous Sinus Thrombosis
- Type
- article
- Field-Weighted Citation Impact
- 0.37