PHARMACEUTICO-ANALYTICAL STUDY OF SHIGRUPUNARNAVADI YOGA: A POLY-HERBAL PREPARATION

Introduction: Shigrupunarnavadi yoga is explained in prayoga samuchayyam, a renowned visha chikitsa grantha (Ayurvedic toxicology book) stating in detail about keraliya visha chikitsa prayogas (traditional Kerala toxicology treatment modalities) authored by Sri Kochunni Thampuran in the context of mandali visha chikitsa (viper bite management) as an external lepa (application). All the ten ingredients in this yoga are economical and readily available. Materials and Methods: This combination of Shigrupunarnavadi yoga has drugs such as Shigru, Punarnava, Haridra, Vacha, Chandana, Patha, Ishwaramooli, Yashtimadhu, Sirisha and Gokshura. Equal drug quantities were combined and processed into kwatha choorna (coarse powder). An analytical study was then conducted following the guidelines outlined in the Ayurvedic Pharmacopoeia of India. Various physicochemical parameters of the kwatha choorna were analysed, including organoleptic characteristics, moisture content, total ash, acid-insoluble ash, water-soluble ash, alcohol-soluble extractive value, and water-soluble extractive value. Additionally, the pH, refractive index, total solids, specific gravity, and viscosity of the freshly prepared Shigrupunarnavadi kwatha (decoction) were assessed. Observation and Results: The phytochemical analytical study proved its efficacy for internal consumption. Conclusion: This study helped standardise Shigrupunarnavadi yoga in kwatha choorna (coarse powder) and kwatha (decoction). It also helped to analyse this particular yoga's probable mode of action when given internally.