Chiral Sodium Glycerophosphate Catalyst for Enantioselective Michael Reactions of Chalcones
A chiral sodium glycerophosphate is successfully exploited as a catalyst in the Michael addition of methyl malonate to a number of chalcones. The reactions supplied the target adducts in satisfactory yields and good enantiomeric excesses. A tentative computational study is presented, aiming to understand the reaction mechanism.
Authors
- Giovanni Ghigo (ORCID: https://orcid.org/0000-0002-2480-5415)
- Stefano Dughera (ORCID: https://orcid.org/0000-0002-6334-9897)
- Julia Rivella
- Alessio Robiolio Bose
Institutions
- University of Turin (IT)
Publication Details
- Journal
- Molecules
- Published
- 2024-10-08
- DOI
- https://doi.org/10.3390/molecules29194763
- Citations
- 1
- Primary Topic
- Chemical Synthesis and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.23
Funders
- Dipartimenti di Eccellenza
- Ministero dell’Istruzione, dell’Università e della Ricerca
- Università degli Studi di Torino
- Ministero dell'Università e della Ricerca