Acute Implantation of a Bioresorbable Polymer Scaffold in Patients With Complete Thoracic Spinal Cord Injury: A Randomized Controlled Trial (INSPIRE 2.0)
In this small group of patients with thoracic complete (AIS A) SCI, implantation of an intraparenchymal bioresorbable scaffold did not produce probable clinical benefit. However, this study provides evidence that surgical intervention in an injured spinal cord parenchyma may be performed safely.
Authors
- David O. Okonkwo (ORCID: https://orcid.org/0000-0002-7444-2851)
- Richard M. Toselli (ORCID: https://orcid.org/0000-0003-0026-4615)
- K. Stuart Lee (ORCID: https://orcid.org/0000-0001-6662-0008)
- James S. Harrop (ORCID: https://orcid.org/0000-0002-0943-3406)
- Kee D. Kim (ORCID: https://orcid.org/0000-0002-0788-0288)
- Ira M. Goldstein (ORCID: https://orcid.org/0000-0003-2443-0315)
Institutions
- Rutgers, The State University of New Jersey (US)
- Prisma Health (US)
- Thomas Jefferson University (US)
- University of Pittsburgh Medical Center (US)
- Center for Discovery (US)
- Neurological Surgery (US)
- Rutgers New Jersey Medical School (US)
- University of California, Davis (US)
Publication Details
- Journal
- Neurosurgery
- Published
- 2024-10-08
- DOI
- https://doi.org/10.1227/neu.0000000000003180
- Citations
- 5
- Primary Topic
- Spinal Cord Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 2.12
Funders
- Brown University
- University of California, San Diego