Integrative bioinformatics analysis for identifying the mitochondrial-related gene signature associated with immune infiltration in premature ovarian insufficiency

Our results highlight the crosstalk between mitochondrial function and the immune response in the development of POI. The identification of MitoDEGs could lead to reliable biomarkers for the early diagnosis, monitoring, and personalized treatment of POI.

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Publication Details

Journal
BMC Medicine
Published
2024-10-08
DOI
https://doi.org/10.1186/s12916-024-03675-7
Citations
5
Primary Topic
Reproductive Biology and Fertility
Type
article
Field-Weighted Citation Impact
2.71
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article

Integrative bioinformatics analysis for identifying the mitochondrial-related gene signature associated with immune infiltration in premature ovarian insufficiency

Xiaolan Zhu, Wenxin Li, Minjun Lu, Jiamin Zhou et al.
5 citations
BMC Medicine
Reproductive Biology and Fertility
2.71
article

Integrative bioinformatics analysis for identifying the mitochondrial-related gene signature associated with immune infiltration in premature ovarian insufficiency

Xiaolan Zhu, Wenxin Li, Minjun Lu, Jiamin Zhou, Li Lin, Junyu Shang, Yueqin Liu
article en
5 citations

Abstract

Our results highlight the crosstalk between mitochondrial function and the immune response in the development of POI. The identification of MitoDEGs could lead to reliable biomarkers for the early diagnosis, monitoring, and personalized treatment of POI.

BMC MedicineVol. 22(1)
Jiangsu University (CN), Affiliated Hospital of Jiangsu University (CN)
Zero hunger
Openalex Percentile: Top 9%
Reproductive Biology and Fertility
2.71
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