IMPC-based screening revealed that ROBO1 can regulate osteoporosis by inhibiting osteogenic differentiation
Our study provides several novel molecular mechanisms involved in the pathogenesis of osteoporosis. <i>ROBO1</i> is a potential target for osteoporosis intervention.
Authors
- Youjia Xu (ORCID: https://orcid.org/0000-0002-9826-4324)
- Qiaocheng Zhai (ORCID: https://orcid.org/0000-0003-4532-9427)
- Keyu Zhu (ORCID: https://orcid.org/0000-0003-0351-7155)
- Y. Wang (ORCID: https://orcid.org/0009-0007-7315-0682)
- Xiangzheng Zhang (ORCID: https://orcid.org/0009-0008-7700-5746)
- Ruizhi Zhang (ORCID: https://orcid.org/0000-0002-8136-3529)
- Wei Qi (ORCID: https://orcid.org/0000-0002-4252-2953)
- Zheng Miao
Institutions
- Wenzhou Medical University (CN)
- Soochow University (CN)
- Second Affiliated Hospital of Soochow University (CN)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2024-10-08
- DOI
- https://doi.org/10.3389/fcell.2024.1450215
- Citations
- 3
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.86
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Zhejiang Province