Effects of normal saline versus lactated Ringer’s solution on organ function and inflammatory responses to heatstroke in rats
NS resuscitation in heat-exposed rats significantly promotes metabolic acidosis and the inflammatory response, leading to greater functional and structural organ damage than does LR. These findings underscore the necessity of selecting appropriate resuscitation fluids for heatstroke management to minimize organ damage and improve outcomes.
Authors
- Chang Liu (ORCID: https://orcid.org/0000-0002-9379-0130)
- Lan Chen (ORCID: https://orcid.org/0000-0003-2971-0498)
- Yuping Zhang (ORCID: https://orcid.org/0009-0008-8781-976X)
- Xiuqin Feng
- Zhaocai Zhang (ORCID: https://orcid.org/0000-0002-1795-5634)
Institutions
- Second Affiliated Hospital of Zhejiang University (CN)
Publication Details
- Journal
- Journal of Intensive Care
- Published
- 2024-10-08
- DOI
- https://doi.org/10.1186/s40560-024-00746-y
- Citations
- 3
- Primary Topic
- Climate Change and Health Impacts
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China
- Natural Science Foundation of Zhejiang Province