Oxidative Stress, Inflammation, and Altered Lymphocyte E-NTPDase Are Implicated in Acute Dyslipidemia in Rats: Protective Role of Arbutin
ARB possessed anti-dyslipidemia, anti-inflammatory, and antioxidant effects mediated via the modulation of CHOL and TG synthesis, LPL, lymphocyte E-NTPDase and E-ADA, and cytokine release in rats. Thus, ARB could be an effective agent to attenuate dyslipidemia and its associated OS and inflammation, pending further studies as well as clinical trials.
Authors
- Emad H. M. Hassanein (ORCID: https://orcid.org/0000-0003-4865-2342)
- Ayman M. Mahmoud (ORCID: https://orcid.org/0000-0003-0279-6500)
- Mousa O. Germoush
- Sulaiman Mohammed Alnasser (ORCID: https://orcid.org/0000-0001-8678-5029)
- Omnia E. Hussein (ORCID: https://orcid.org/0000-0002-9811-7519)
- Meshal Alotaibi (ORCID: https://orcid.org/0000-0002-9823-3333)
- Mohamed El Mohtadi (ORCID: https://orcid.org/0000-0002-5707-6415)
- Reem S. Alruhaimi (ORCID: https://orcid.org/0000-0003-3746-8582)
Institutions
- Princess Nourah bint Abdulrahman University (SA)
- Beni-Suef University (EG)
- Manchester Metropolitan University (GB)
- Qassim University (SA)
- Higher Technological Institute (EG)
- Edge Hill University (GB)
- Al-Azhar University (EG)
- Jouf University (SA)
- University of Hafr Al-Batin (SA)
Publication Details
- Journal
- Pharmaceuticals
- Published
- 2024-10-08
- DOI
- https://doi.org/10.3390/ph17101343
- Citations
- 5
- Primary Topic
- Cholesterol and Lipid Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 2.86
Funders
- Princess Nourah Bint Abdulrahman University