Differences in safety profiles of anti-herpesvirus medications: a real-world pharmacovigilance study based on the FAERS database
Our study revealed differences in safety profiles of four anti-herpesvirus medications. Ganciclovir exhibited the highest risk of hematotoxicity but appeared relatively safe in seizures and SCARs. Foscarnet was more likely to induce nephrotoxicity, seizures, and electrolyte imbalances than others. Acyclovir and valaciclovir were strongly associated with plasmacytosis, neurotoxicity, and SCARs.
Authors
- Dexuan Kong
- Yanbin Zeng
- Shunguo Zhang
- He Dan
- Zhiling Li (ORCID: https://orcid.org/0000-0002-1467-0641)
- Meifen Han
Institutions
- Shanghai Jiao Tong University (CN)
- Xiamen University (CN)
- Shanghai Children's Medical Center (CN)
- Shengli Oilfield Central Hospital (CN)
Publication Details
- Journal
- Expert Opinion on Drug Safety
- Published
- 2024-10-08
- DOI
- https://doi.org/10.1080/14740338.2024.2412235
- Citations
- 1
- Primary Topic
- Herpesvirus Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.39