Neurofilament light chain as a biomarker for hereditary ATTR amyloidosis − correlation between neurofilament light chain and nerve conduction study
NfL levels are found to be correlated with CMAP/SNAP amplitudes. Compared with NCS, NfL can be a more sensitive biomarker for detecting treatment response and active nerve damage even in patients with advanced neuropathy.
Authors
- Minori Kodaira (ORCID: https://orcid.org/0000-0003-2954-9550)
- Akira Matsushima
- Emre Aldinc (ORCID: https://orcid.org/0000-0002-7237-4760)
- Yoshiki Sekijima (ORCID: https://orcid.org/0000-0002-8132-2743)
- Gang Jia (ORCID: https://orcid.org/0000-0003-1102-0683)
- Yusuke Mochizuki (ORCID: https://orcid.org/0000-0002-3415-2796)
- Simina Ticau (ORCID: https://orcid.org/0000-0003-1096-9627)
- Yusuke Takahashi
- Ken Takasone
- Masateru Tajiri
- Mitsuto Sato
Institutions
- Shinshu University (JP)
- Alnylam Pharmaceuticals (United States) (US)
Publication Details
- Journal
- Amyloid
- Published
- 2024-10-01
- DOI
- https://doi.org/10.1080/13506129.2024.2409760
- Citations
- 3
- Primary Topic
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.70