Association of various RAS codon mutations and prognostic outcomes of patients with colorectal liver metastases after hepatectomy

KRAS Q61 and NRAS Q61 mutations are promising predictors for OS in CRLM patients after hepatectomy. Postoperative chemotherapy may significantly benefit CRLM patients with RAS mutations, particularly those identified as high-risk.

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Publication Details

Journal
Cancer Medicine
Published
2024-10-01
DOI
https://doi.org/10.1002/cam4.70168
Citations
2
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
Field-Weighted Citation Impact
0.74

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article

Association of various RAS codon mutations and prognostic outcomes of patients with colorectal liver metastases after hepatectomy

Baocai Xing, X L Wu, Kun Wang, Yanyan Wang et al.
2 citations
Cancer Medicine
Hepatocellular Carcinoma Treatment and Prognosis
0.74
article

Association of various RAS codon mutations and prognostic outcomes of patients with colorectal liver metastases after hepatectomy

Baocai Xing, X L Wu, Kun Wang, Yanyan Wang, Wei Liu
article en
2 citations

Abstract

KRAS Q61 and NRAS Q61 mutations are promising predictors for OS in CRLM patients after hepatectomy. Postoperative chemotherapy may significantly benefit CRLM patients with RAS mutations, particularly those identified as high-risk.

Cancer MedicineVol. 13(19)
Peking University (CN), Peking University Cancer Hospital (CN)
National Natural Science Foundation of China
No poverty
Openalex Percentile: Top 27%
Hepatocellular Carcinoma Treatment and Prognosis
0.74
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