IPECAD Modeling Workshop 2023 Cross-Comparison Challenge on Cost-Effectiveness Models in Alzheimer’s Disease
Trial data can be implemented in different ways across health-economic models leading to large variation in model predictions. We recommend (1) addressing the choice of outcome measure and treatment effectiveness assumptions in sensitivity analysis, (2) a standardized reporting table for model predictions, and (3) exploring the use of registries for future AD treatments measuring long-term disease progression to reduce uncertainty of extrapolating short-term trial results by health-economic models.
Authors
- Peter Pemberton‐Ross (ORCID: https://orcid.org/0000-0002-6739-1873)
- Linus Jönsson (ORCID: https://orcid.org/0000-0001-5751-6292)
- Anders Gustavsson (ORCID: https://orcid.org/0000-0002-2147-2969)
- Jakub Hlávka (ORCID: https://orcid.org/0000-0002-2766-390X)
- Eldon Spackman (ORCID: https://orcid.org/0000-0001-8558-5973)
- Lars Lau Rakêt (ORCID: https://orcid.org/0000-0001-7099-2314)
- Ashley Tate (ORCID: https://orcid.org/0000-0002-4523-6960)
- Sandar Aye (ORCID: https://orcid.org/0000-0003-1360-4834)
- William L. Herring (ORCID: https://orcid.org/0000-0001-8222-9914)
- Myriam Soto‐Gordoa (ORCID: https://orcid.org/0000-0002-3582-4283)
- F. Kamgar
- M. Urbich
- Javier Mar (ORCID: https://orcid.org/0000-0002-9455-4869)
- Anders Sköldunger (ORCID: https://orcid.org/0000-0001-8439-2248)
- Chiara C. Brück (ORCID: https://orcid.org/0000-0001-5677-269X)
- Bengt Winblad (ORCID: https://orcid.org/0000-0002-0011-1179)
- Ron L. H. Handels (ORCID: https://orcid.org/0000-0002-8663-0630)
- Anders Wimo (ORCID: https://orcid.org/0000-0003-0963-5750)
- Chelsea Bedrejo Stellick
- Colin Green (ORCID: https://orcid.org/0000-0001-6156-4676)
- Robert M. Anderson (ORCID: https://orcid.org/0000-0002-8580-9663)
- Yifan Wei (ORCID: https://orcid.org/0000-0002-8870-7304)
- Inge de Kok
Institutions
- Karolinska University Hospital (SE)
- Mondragon Unibertsitatea (ES)
- Lund University (SE)
- Erasmus MC (NL)
- Karolinska Institutet (SE)
- RTI Health Solutions (US)
- Biogen (Switzerland) (CH)
Publication Details
- Journal
- Value in Health
- Published
- 2024-10-08
- DOI
- https://doi.org/10.1016/j.jval.2024.09.006
- Citations
- 4
- Primary Topic
- Health Systems, Economic Evaluations, Quality of Life
- Type
- article
- Field-Weighted Citation Impact
- 4.52
Funders
- Karolinska Institutet
- National Institutes of Health