Enhancing Omicron Sublineage Neutralization: Insights From Bivalent and Monovalent COVID‐19 Booster Vaccines and Recent SARS‐CoV‐2 Omicron Variant Infections
This study underscores the intricate interplay between vaccination strategies, immune imprinting, and the dynamic landscape of SARS-CoV-2 variants. Although bivalent boosters enhance neutralization, addressing the challenge of emerging sublineages like XBB.1.17.1, FK.1.1, and JN.1 may necessitate the development of tailored vaccines, underscoring the need for ongoing adaptation to effectively combat this highly mutable virus.
Authors
- Mark Anthony B. Casel (ORCID: https://orcid.org/0000-0002-8313-4076)
- Hee‐Sung Kim (ORCID: https://orcid.org/0000-0001-7559-4438)
- Rare Rollon (ORCID: https://orcid.org/0000-0002-8428-1713)
- Hye Won Jeong (ORCID: https://orcid.org/0000-0002-1063-8476)
- Juryeon Gil (ORCID: https://orcid.org/0000-0002-9415-0688)
- Seung‐Gyu Jang (ORCID: https://orcid.org/0000-0001-9316-1652)
- Young Ki Choi (ORCID: https://orcid.org/0000-0002-0872-0147)
- Hyunwoo Jang (ORCID: https://orcid.org/0009-0002-9284-8473)
- Jeong Ho Choi
- Jun Hyoung Kim (ORCID: https://orcid.org/0000-0002-0595-2110)
- Se‐Mi Kim (ORCID: https://orcid.org/0000-0001-7932-1381)
- Josea Carmel Lazarte
Institutions
- Chungbuk National University (KR)
- Institute for Basic Science (KR)
- Chungbuk National University Hospital (KR)
Publication Details
- Journal
- Influenza and Other Respiratory Viruses
- Published
- 2024-10-01
- DOI
- https://doi.org/10.1111/irv.70000
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation
- National Research Foundation of Korea