Role of KIM-1 in early diagnosis of contrast-induced nephropathy following invasive cardiac procedure: A systematic review

This systematic review aims to provide a comprehensive analysis of the diagnostic efficacy of KIM-1 in CI-AKI.We evaluated its potential as a robust biomarker for the early identification and prediction of AKI progression.Methodology: To assess KIM-1 as a biomarker for CI-AKI, relevant databases were searched.Inclusion criteria comprised studies measuring KIM-1 levels in patients undergoing cardiac procedures with contrast media and data were extracted.Methodological quality and bias were evaluated using Quadas-2 tool.Conclusion: KIM-1 shows promise as a biomarker for renal injury.Its upregulation, correlation with injury severity, and involvement in tissue repair support its clinical relevance.