The Association of Interleukin‐36 Staining Intensity and Response to Biologic Therapy in Patients With Psoriasis: A Retrospective Immunohistochemical and Chart Review Pilot Study

Patients with psoriasis with high IL-36 expression were more likely to respond to IL-12/23 and IL-23 inhibition than those with low IL-36, though these findings were not statistically significant. Additional studies with larger sample sizes are needed to validate and expand upon these findings.

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Publication Details

Journal
Journal of Cutaneous Pathology
Published
2024-10-08
DOI
https://doi.org/10.1111/cup.14729
Citations
1
Primary Topic
Psoriasis: Treatment and Pathogenesis
Type
article
Field-Weighted Citation Impact
0.24
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article

The Association of Interleukin‐36 Staining Intensity and Response to Biologic Therapy in Patients With Psoriasis: A Retrospective Immunohistochemical and Chart Review Pilot Study

William R. Zhang, Tina Bhutani, Jeffrey P. North
1 citations
Journal of Cutaneous Pathology
Psoriasis: Treatment and Pathogenesis
0.24
article

The Association of Interleukin‐36 Staining Intensity and Response to Biologic Therapy in Patients With Psoriasis: A Retrospective Immunohistochemical and Chart Review Pilot Study

William R. Zhang, Tina Bhutani, Jeffrey P. North
article en
1 citations

Abstract

Patients with psoriasis with high IL-36 expression were more likely to respond to IL-12/23 and IL-23 inhibition than those with low IL-36, though these findings were not statistically significant. Additional studies with larger sample sizes are needed to validate and expand upon these findings.

Journal of Cutaneous PathologyVol. 52(1)
University of California, San Francisco (US)
Good health and well-being
Openalex Percentile: Top 42%
Psoriasis: Treatment and Pathogenesis
0.24
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