Evaluating the Impact of a Complex Volume Conductor Model on Network Dynamics for Deep Brain Stimulation

Computational modelling of deep brain stimulation for obsessive-compulsive disorder is vital for understanding the complex neural mechanisms underlying the disorder and for optimising treatment efficacy. This work presents a computational study investigating the intricate relationship between an advanced volume conductor model and a biophysical network model of the striatum in modelling deep brain stimulation. We highlight the pivotal role of integrating complex volume conductor models with neural network simulations and provide insights into their profound impact on understanding brain activity.

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Publication Details

Published
2024-09-02
DOI
https://doi.org/10.1109/iceaa61917.2024.10701721
Primary Topic
Neurological disorders and treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Evaluating the Impact of a Complex Volume Conductor Model on Network Dynamics for Deep Brain Stimulation

Ursula van Rienen, Rüdiger Köhling, Jens Starke, Jan Philipp Payonk et al.
Neurological disorders and treatments
article

Evaluating the Impact of a Complex Volume Conductor Model on Network Dynamics for Deep Brain Stimulation

Ursula van Rienen, Rüdiger Köhling, Jens Starke, Jan Philipp Payonk, Revathi Appali, Konstantinos Spiliotis
article en

Abstract

Computational modelling of deep brain stimulation for obsessive-compulsive disorder is vital for understanding the complex neural mechanisms underlying the disorder and for optimising treatment efficacy. This work presents a computational study investigating the intricate relationship between an advanced volume conductor model and a biophysical network model of the striatum in modelling deep brain stimulation. We highlight the pivotal role of integrating complex volume conductor models with neural network simulations and provide insights into their profound impact on understanding brain activity.

University of Rostock (DE)
Deutsche Forschungsgemeinschaft
Openalex Percentile: Top 73%
Neurological disorders and treatments
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