An Unexpected Access to Phospholene Fused β-Phosphinolactams by the Reaction of α-C<sub>2</sub>-Bridged Biphospholes and Nitrones
An efficient and practical method for the preparation of the phospholene fused β-phosphinolactam skeleton from α-C<sub>2</sub>-bridged biphospholes and nitrones is described. The dissociation of biphospholes generates transient 1-phosphafulvenes, followed by oxidation with nitrones to give the 1-phosphafulvene oxides. The oxidation of 1-phosphafulvene boosts its reactivity toward imine, leading to the isolated products.
Authors
- Yu Ji (ORCID: https://orcid.org/0000-0003-3752-8389)
- Rongqiang Tian (ORCID: https://orcid.org/0000-0002-5460-1691)
- Hui Zhang (ORCID: https://orcid.org/0000-0002-4198-2042)
- Jiawei Li (ORCID: https://orcid.org/0000-0003-4416-0404)
- Yanjie Liu
- Chunjie Wang (ORCID: https://orcid.org/0000-0003-0503-9820)
- Xiaobing Liu (ORCID: https://orcid.org/0000-0002-0680-1947)
Institutions
- Zhengzhou University (CN)
- Zhoukou Normal University (CN)
Publication Details
- Journal
- Organic Letters
- Published
- 2024-10-08
- DOI
- https://doi.org/10.1021/acs.orglett.4c03062
- Citations
- 4
- Primary Topic
- Synthesis and characterization of novel inorganic/organometallic compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.63
Funders
- Zhoukou Normal University