Intrinsic cardiomyopathy in pediatric Marfan syndrome: predictive factors and risk assessments
The objective of this study was to elucidate the contentious issue of intrinsic cardiomyopathy in Marfan syndrome and demonstrate its notable occurrence even in pediatric patients who do not exhibit heart failure symptoms or valvular complications. We highlighted the importance of specific FBN1 variants and higher systemic scores in identifying the potential for intrinsic cardiomyopathy in pediatric patients with Marfan syndrome.
Authors
- Ingeborg Friehs (ORCID: https://orcid.org/0000-0002-2631-2972)
- Daniel Diaz‐Gil (ORCID: https://orcid.org/0000-0002-4179-5570)
- Thomas S. Mir (ORCID: https://orcid.org/0000-0002-8337-5187)
- M. Hübler (ORCID: https://orcid.org/0000-0001-7672-8629)
- V. Stark (ORCID: https://orcid.org/0000-0003-3978-1804)
- Rainer Kozlik‐Feldmann (ORCID: https://orcid.org/0000-0002-6222-2683)
- J. Olfe (ORCID: https://orcid.org/0000-0002-4449-7739)
- Kerstin Kutsche
- Yskert von Kodolitsch
- Jonas Kneußel
Institutions
- Boston University (US)
- Boston Children's Hospital (US)
- Harvard University (US)
- Universität Hamburg (DE)
- University Medical Center Hamburg-Eppendorf (DE)
Publication Details
- Journal
- Pediatric Research
- Published
- 2024-10-08
- DOI
- https://doi.org/10.1038/s41390-024-03613-6
- Citations
- 1
- Primary Topic
- Connective tissue disorders research
- Type
- article
- Field-Weighted Citation Impact
- 0.55