Systematic screening of protein-coding gene expression identified VWF as a potential key regulator in anthracycline-based chemotherapy-exacerbated metastasis of breast cancer
Doxorubicin-exacerbated evasion and migration through VWF upregulation. Berberine as an inhibitor of VWF was able to reversed the doxorubicin-exacerbated VWF upregulation and evasion and migration in breast cancer cells.
Authors
- Xuehan Yang
- Yawei Zhao (ORCID: https://orcid.org/0000-0002-1689-5406)
- Meihui He
- Jianhua Dong (ORCID: https://orcid.org/0000-0002-6532-3762)
- Lianzhi Cui
- Li Chen (ORCID: https://orcid.org/0000-0003-0738-5161)
- Min Zhang (ORCID: https://orcid.org/0000-0001-8107-5212)
- Kan He (ORCID: https://orcid.org/0000-0003-1966-4088)
- Hansi Zhang
- Xu Yang (ORCID: https://orcid.org/0000-0003-2242-670X)
- Tianyu Zhao (ORCID: https://orcid.org/0000-0002-4424-7959)
Institutions
- Jilin University (CN)
- Jilin Province Tumor Hospital (CN)
- Jilin Medical University (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2024-10-08
- DOI
- https://doi.org/10.1186/s12885-024-12999-9
- Primary Topic
- Cancer-related Molecular Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Jilin University
- Education Department of Jilin Province