Fungal toxin fusicoccin enhances plant growth by upregulating 14-3-3 interaction with plasma membrane H+-ATPase
Fusicoccin-A (FC-A) is a diterpene glucoside produced by a pathogenic fungus. Since its discovery, FC-A has been widely recognized as a phytotoxin that induces stomatal opening and leaf wilting, eventually leading to plant death. In this study, we present the first evidence that FC-A enhances plant growth by stabilizing the protein-protein interaction between plasma membrane (PM) H<sup>+</sup>-ATPase and 14-3-3 in guard cells. Long-term treatment of Arabidopsis plants with FC-A resulted in ~ 30% growth enhancement. Structurally similar fusicoccin-J (FC-J) showed a similar degree of growth-promotion activity as FC-A, whereas the more hydrophilic fusicoccin-H (FC-H) exhibited no effect on plant growth, indicating that the enhancement of plant growth observed with FC-A and FC-J involves upregulation of the protein-protein interaction between PM H<sup>+</sup>-ATPase and 14-3-3 in guard cells, which promotes stomatal opening and photosynthesis.
Authors
- Hiroki Irieda (ORCID: https://orcid.org/0000-0002-4545-9187)
- Shigemitsu Kasuga
- Satoru Kinoshita (ORCID: https://orcid.org/0000-0003-4687-5630)
- Toshinori Kinoshita (ORCID: https://orcid.org/0000-0001-7621-1259)
- Junko Ohkanda (ORCID: https://orcid.org/0000-0001-9663-5104)
- Yuki Hayashi
- Rikako Honda
- Hironaru Kiriyama
Institutions
- Shinshu University (JP)
- Nagoya University (JP)
Publication Details
- Journal
- Scientific Reports
- Published
- 2024-10-08
- DOI
- https://doi.org/10.1038/s41598-024-73979-4
- Citations
- 4
- Primary Topic
- 14-3-3 protein interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- Japan Society for Bioscience, Biotechnology, and Agrochemistry
- Ministry of Education, Culture, Sports, Science and Technology
- Japan Student Services Organization
- Shinshu University
- Japan Society for the Promotion of Science