Identification of the effects of hypoxia on the liver tissues of Nile tilapia Oreochromis Niloticus
The Nile tilapia strain improves the abilities of hypoxia response through energy metabolism. Antioxidant enzyme measurements in the liver indicate that these five antioxidant enzymes play important roles in protecting the body from hypoxic damage. The histological changes in liver cells indicate that the damage caused by hypoxia stress. The immune-related metabolic pathways and energy metabolism-related pathways were obtained by transcriptome profiling, and these metabolic pathways and the differentially expressed genes selected from these metabolic pathways may be involved in the mechanism of hypoxia tolerance in this strain. These findings provide a better understanding of the hypoxia response mechanism of fish, and represent a useful resource for the genetic breeding of O. niloticus.
Authors
- Hong Yang (ORCID: https://orcid.org/0000-0001-9526-6204)
- Junquan Zhu (ORCID: https://orcid.org/0000-0001-5908-3777)
- Wei Xiao (ORCID: https://orcid.org/0000-0001-5660-678X)
- Zhiying Zou (ORCID: https://orcid.org/0000-0003-0661-4348)
- Chengliang Wei
- Dayu Li (ORCID: https://orcid.org/0000-0002-7845-3638)
- Jinglin Zhu (ORCID: https://orcid.org/0000-0001-6511-1615)
- Jie Yu (ORCID: https://orcid.org/0000-0001-6606-5462)
- Binglin Chen (ORCID: https://orcid.org/0000-0002-7434-2551)
Institutions
- Ningbo University (CN)
- Ministry of Agriculture and Rural Affairs (CN)
- Chinese Academy of Fishery Sciences (CN)
Publication Details
- Journal
- BMC Genomics
- Published
- 2024-10-08
- DOI
- https://doi.org/10.1186/s12864-024-10700-9
- Citations
- 6
- Primary Topic
- Physiological and biochemical adaptations
- Type
- article
- Field-Weighted Citation Impact
- 2.75
Funders
- National Natural Science Foundation of China
- Central Public-interest Scientific Institution Basal Research Fund, Chinese Academy of Fishery Sciences