Single-cell dissection reveals promotive role of ENO1 in leukemia stem cell self-renewal and chemoresistance in acute myeloid leukemia
Our findings underscore the critical role of ENO1 as a plausible driver of LSC self-renewal, a potential target for AML target therapy and a biomarker for AML prognosis.
Authors
- Yun Tian (ORCID: https://orcid.org/0000-0003-1475-309X)
- Oscar Junhong Luo (ORCID: https://orcid.org/0000-0002-1266-3069)
- Lipeng Mao (ORCID: https://orcid.org/0000-0002-0155-6700)
- Zhixi Chen (ORCID: https://orcid.org/0000-0002-5900-8467)
- Xianfeng Zha (ORCID: https://orcid.org/0000-0002-4970-1305)
- Yangqiu Li (ORCID: https://orcid.org/0000-0002-0974-4036)
- Jiafan Guo
- Xingwei Zhang (ORCID: https://orcid.org/0000-0002-0837-9890)
- Yikai Zhang (ORCID: https://orcid.org/0000-0002-6851-6260)
Institutions
- Jinan University (CN)
- Ministry of Education (ME)
- Ministry of Agriculture (CA)
- First Affiliated Hospital of Jinan University (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2024-10-08
- DOI
- https://doi.org/10.1186/s13287-024-03969-w
- Citations
- 4
- Primary Topic
- Renal and related cancers
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Jinan University
- K. C. Wong Education Foundation
- Pearl River S and T Nova Program of Guangzhou
- Basic and Applied Basic Research Foundation of Guangdong Province