Serum lncRNA ITGB2-AS1 and ICAM-1 as novel biomarkers for rheumatoid arthritis and osteoarthritis diagnosis
Our study portrays serum ITGB2-AS1 as a novel potential diagnostic biomarker of RA that correlates with disease activity. A predictive panel combining ITGB2-AS1 and ICAM-1 could have clinical utility in RA diagnosis. We also spotlight the association of ICAM-1 with knee OA diagnosis. The correlation of serum ITGB2-AS1 with ITGB2 expression in both diseases may be insightful for further mechanistic studies.
Authors
- Yumn A. Elsabagh
- Mahmoud A. Senousy
- Maha M. El‐Sawalhi (ORCID: https://orcid.org/0000-0002-6598-4392)
- Nabila A. Ismail
- Aliaa M. Selim
Institutions
- Cairo University (EG)
- Egyptian Russian University (EG)
Publication Details
- Journal
- BMC Medical Genomics
- Published
- 2024-10-08
- DOI
- https://doi.org/10.1186/s12920-024-01993-6
- Citations
- 10
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 2.85
Funders
- Cairo University
- Faculty of Pharmacy, Cairo University