IL-7Rα on CD4+ T cells is required for their survival and the pathogenesis of experimental autoimmune encephalomyelitis
Our study demonstrates that IL-7Rα on peripheral CD4<sup>+</sup> T cells is essential for their maintenance, immune response, and EAE pathogenesis.
Authors
- Reza Yazdani (ORCID: https://orcid.org/0000-0002-3760-4137)
- Hamed Naziri (ORCID: https://orcid.org/0000-0001-6290-8944)
- Bogoljub Ćirić (ORCID: https://orcid.org/0000-0001-5361-7635)
- Abdolmohamad Rostami (ORCID: https://orcid.org/0000-0003-0716-2726)
- Bram Van den Broek (ORCID: https://orcid.org/0000-0003-4624-4812)
- Gholamreza Azizi (ORCID: https://orcid.org/0000-0001-5658-2511)
- Larissa Lumi Watanabe Ishikawa (ORCID: https://orcid.org/0000-0003-3481-2181)
- Guang‐Xian Zhang (ORCID: https://orcid.org/0000-0003-0017-5997)
Institutions
- Thomas Jefferson University (US)
Publication Details
- Journal
- Journal of Neuroinflammation
- Published
- 2024-10-08
- DOI
- https://doi.org/10.1186/s12974-024-03224-2
- Citations
- 10
- Primary Topic
- T-cell and B-cell Immunology
- Type
- article
- Field-Weighted Citation Impact
- 2.40
Funders
- Thomas Jefferson University
- National Institutes of Health