Cortical morphological changes and associated transcriptional signatures in post-traumatic stress disorder and psychological resilience

The formation of resilience may be by an active compensatory process of the brain. The combination of macroscopic neuroimaging changes and microscopic human brain transcriptomics could offer a more direct and in-depth understanding of the pathogenesis of PTSD and psychological resilience, shedding light on new targets for the prevention and treatment of PTSD.

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Publication Details

Journal
BMC Medicine
Published
2024-10-08
DOI
https://doi.org/10.1186/s12916-024-03657-9
Citations
9
Primary Topic
Functional Brain Connectivity Studies
Type
article
Field-Weighted Citation Impact
3.08

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article

Cortical morphological changes and associated transcriptional signatures in post-traumatic stress disorder and psychological resilience

Minlan Yuan, Hongru Zhu, Wei Zhang, Bo Zheng et al.
9 citations
BMC Medicine
Functional Brain Connectivity Studies
3.08
article

Cortical morphological changes and associated transcriptional signatures in post-traumatic stress disorder and psychological resilience

Minlan Yuan, Hongru Zhu, Wei Zhang, Bo Zheng, Su Lui, Lun Li
article en
9 citations

Abstract

The formation of resilience may be by an active compensatory process of the brain. The combination of macroscopic neuroimaging changes and microscopic human brain transcriptomics could offer a more direct and in-depth understanding of the pathogenesis of PTSD and psychological resilience, shedding light on new targets for the prevention and treatment of PTSD.

BMC MedicineVol. 22(1)
Sichuan University (CN), West China Medical Center of Sichuan University (CN), Chengdu Institute of Information Technology (China) (CN), West China Hospital of Sichuan University (CN), Sichuan Mianyang 404 Hospital (CN)
National Natural Science Foundation of China, Department of Science and Technology of Sichuan Province, Sichuan University, West China Hospital, Sichuan University
Climate action
Openalex Percentile: Top 8%
Functional Brain Connectivity Studies
3.08
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