Blood trauma in veno-venous extracorporeal membrane oxygenation: low pump pressures and low circuit resistance matter
Integrating in-silico predictions with clinical data provided a novel approach in understanding and potentially reducing blood trauma in VV ECMO. This study further demonstrated that a key factor in lowering side effects of ECMO support is the maintenance of low circuit resistance, including oxygenators with the lowest possible resistance, the shortest feasible circuit tubing, and cannulae with an optimal diameter.
Authors
- Christopher Blum (ORCID: https://orcid.org/0009-0006-1190-9369)
- Michael Neidlin (ORCID: https://orcid.org/0000-0002-5582-6905)
- Christian Karagiannidis (ORCID: https://orcid.org/0000-0003-3247-2849)
- Ulrich Steinseifer (ORCID: https://orcid.org/0000-0002-8065-9803)
- Micha Landoll
- Stephan Straßmann
Institutions
- Witten/Herdecke University (DE)
- University Hospital Cologne (DE)
- RWTH Aachen University (DE)
Publication Details
- Journal
- Critical Care
- Published
- 2024-10-08
- DOI
- https://doi.org/10.1186/s13054-024-05121-9
- Citations
- 11
- Primary Topic
- Mechanical Circulatory Support Devices
- Type
- article
- Field-Weighted Citation Impact
- 2.03
Funders
- Deutsche Forschungsgemeinschaft
- RWTH Aachen University
- Xenios