Serum metabonomics reveal the effectiveness of human placental mesenchymal stem cell therapy for primary sclerosing cholangitis
This study revealed metabolic regulatory changes in PSC model mice after hP-MSC treatment and identified eight promising biomarkers, providing preclinical evidence to support therapeutic applications of hP-MSC.
Authors
- Deying Chen (ORCID: https://orcid.org/0000-0002-3675-474X)
- Qigu Yao (ORCID: https://orcid.org/0000-0002-5425-0481)
- Zhehua Zhang
- Jiong Yu
- Hongcui Cao
- Jun Li (ORCID: https://orcid.org/0000-0002-7236-8088)
- Liang Li (ORCID: https://orcid.org/0000-0001-9139-5025)
- Yingduo Yu
- Qiaoling Pan (ORCID: https://orcid.org/0000-0002-3771-8193)
Institutions
- University of Alberta (CA)
- National Clinical Research Center for Digestive Diseases (CN)
- National Center for Infectious Diseases (US)
- First Affiliated Hospital Zhejiang University (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2024-10-08
- DOI
- https://doi.org/10.1186/s13287-024-03967-y
- Citations
- 3
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- National Key Research and Development Program of China
- Fundamental Research Funds for the Central Universities