Contribution of inflammation markers and quantitative sensory testing (QST) indices of central sensitisation to rheumatoid arthritis pain
In individuals with clinically active RA, markers of inflammatory disease activity best explain RA pain with only marginal contributions from QST indices of central sensitisation. Although inflammation plays a key role in the experience of RA pain, the greater proportion of pain severity remains unexplained by DAS28 and ultrasound indices of inflammation.
Authors
- David A. Walsh
- Eamonn Ferguson (ORCID: https://orcid.org/0000-0002-7678-1451)
- Dorothy Platts
- Daniel F. McWilliams (ORCID: https://orcid.org/0000-0002-0581-1895)
- Stephanie L. Smith (ORCID: https://orcid.org/0000-0002-3365-0144)
- Richard J. Wakefield (ORCID: https://orcid.org/0000-0001-5352-8683)
- Vasileios Georgopoulos (ORCID: https://orcid.org/0000-0002-7195-4018)
- Susanne Ledbury
- Deborah Wilson
Institutions
- University of Leeds (GB)
- University of Nottingham (GB)
- Sherwood Forest Hospitals NHS Foundation Trust (GB)
- Nottingham City Hospital (GB)
- NIHR Leeds Musculoskeletal Biomedical Research Unit (GB)
- Arthritis UK (GB)
- Nottingham Biomedical Research Centre (GB)
- Oldham Council (GB)
Publication Details
- Journal
- Arthritis Research & Therapy
- Published
- 2024-10-08
- DOI
- https://doi.org/10.1186/s13075-024-03407-5
- Citations
- 4
- Primary Topic
- Rheumatoid Arthritis Research and Therapies
- Type
- article
- Field-Weighted Citation Impact
- 1.88
Funders
- Pfizer
- Versus Arthritis
- Pfizer UK