<i>Toxoplasma</i> qPCR Kinetics to Guide Preemptive Treatment of Toxoplasmosis After Allogeneic Hematopoietic Stem Cell Transplantation
This study underscores the predictive value of qPCR kinetics monitoring in allo-HCT patients with toxoplasmosis. With the aforementioned risk factors, clinicians can identify patients at high risk for worse outcome. Our results support to consider a therapeutic change or reinforcement if the parasitic load does not decrease after 10 days, supplementing existing clinical guidelines.
Authors
- Andreas H. Groll (ORCID: https://orcid.org/0000-0003-1188-393X)
- Aliénor Xhaard (ORCID: https://orcid.org/0000-0002-4449-989X)
- Stéphane Bretagne
- Robina Aerts (ORCID: https://orcid.org/0000-0001-6337-6636)
- Katrien Lagrou (ORCID: https://orcid.org/0000-0001-8668-1350)
- Christine Robin
- Catherine Cordonnier (ORCID: https://orcid.org/0000-0002-3216-5470)
Institutions
- Université Paris Cité (FR)
- Saint Louis University Hospital (US)
- Temple Street Children's University Hospital (IE)
- Assistance Publique – Hôpitaux de Paris (FR)
- University Hospital Münster (DE)
- Hôpitaux Universitaires Henri-Mondor (FR)
- Hôpital Saint-Louis (FR)
- KU Leuven (BE)
Publication Details
- Journal
- Clinical Infectious Diseases
- Published
- 2024-10-08
- DOI
- https://doi.org/10.1093/cid/ciae488
- Citations
- 2
- Primary Topic
- Toxoplasma gondii Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.03