Peer Review of “Development and Assessment of a Point-of-Care Application (Genomic Medicine Guidance) for Heritable Thoracic Aortic Disease”

This paper [1] describes an application, Genomic Medicine Guidance, a point-of-care tool to deliver concise clinical information about gene mutations that cause heritable cardiovascular diseases. Specific CommentsThis paper provides technical details about the application and its purpose, which is to collate data about genetic/ genomic risks into a readily usable summary of clinical recommendations, particularly for nonexpert clinicians.This seems like a useful resource that could be updated and expanded as time goes on.I have some comments for the authors to address in order to strengthen the manuscript.