Theta-Alpha Variability on EEG Is Associated With Acute Brain Injury in Children and Young Adults With Liver Failure
Depressed TAV on EEG is associated with increased odds of abnormal restricted diffusivity in gray matter on brain MRI in children and young adults hospitalized with liver failure. This MRI finding is seen in scenarios where changes to medical management are time-sensitive (i.e., acute stroke and PRES) or where prognostic discussion may be influenced by MRI findings (hypoxic-ischemic injury). TAV thus has a potential role as an automated, bedside decision support tool for clinicians deciding on the urgency of brain MRI in critically ill patients.
Authors
- Earn-Chun Christabel Lee (ORCID: https://orcid.org/0000-0002-4059-8495)
- Taymour Hashemzadeh
- Nathan Kattapuram (ORCID: https://orcid.org/0000-0002-6766-7235)
- Allan Fong (ORCID: https://orcid.org/0000-0002-7550-1569)
- A. W. Andrews (ORCID: https://orcid.org/0000-0002-2395-5147)
- Sarika Bharil (ORCID: https://orcid.org/0000-0003-1308-3119)
- Jacqueline Barnes (ORCID: https://orcid.org/0009-0009-4191-4080)
Institutions
- MedStar National Rehabilitation Hospital (US)
- Georgetown University (US)
- MedStar Georgetown University Hospital (US)
Publication Details
- Journal
- Neurology Clinical Practice
- Published
- 2024-10-08
- DOI
- https://doi.org/10.1212/cpj.0000000000200389
- Citations
- 1
- Primary Topic
- Liver Disease and Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 0.37