Bitemporal Hemianopia with Optic Chiasm Lesion: An Uncommon Presentation of MOGAD

predominance and elevated CSF protein.COVID-19 PCR was positive.CT, B-scan, and MRI showed bilateral retinal detachment with no optic nerve involvement.Fundus fluorescein angiography of the bilateral retinal vessels revealed mottled hyperfluorescence and hypofluerescence and bilateral fundus autofluorescence associated with retinal pigment epithelium detachment consistent with VKH. ConclusionsVKH is a rare and potentially debilitating disorder in which severe complications can be avoided by early diagnosis and adequate treatment.Mainstay treatment includes corticosteroids and immunosuppressants.Viral infections such as cytomegalovirus (CMV) have been reported to trigger the development of VKH, possibly due to underlying molecular mimicry.COVID-19 was a potential immunological trigger of VKH in our patient, given infection onset was prior to the 2-week history of VKH onset.Although rare, COVID-19 may be considered a precipitant of VKH.

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Publication Details

Journal
Neurology
Published
2024-10-08
DOI
https://doi.org/10.1212/01.wnl.0001051208.91387.34
Primary Topic
Retinal Diseases and Treatments
Type
article
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article

Bitemporal Hemianopia with Optic Chiasm Lesion: An Uncommon Presentation of MOGAD

Sushma Yerram, Paisith Piriyawat, Naila Kausar, Salvador Cruz‐Flores et al.
Neurology
Retinal Diseases and Treatments
article

Bitemporal Hemianopia with Optic Chiasm Lesion: An Uncommon Presentation of MOGAD

Sushma Yerram, Paisith Piriyawat, Naila Kausar, Salvador Cruz‐Flores, Amy Huimin-Gao Sim, Julia Guido, Claudia Prospero Ponce
article en

Abstract

predominance and elevated CSF protein.COVID-19 PCR was positive.CT, B-scan, and MRI showed bilateral retinal detachment with no optic nerve involvement.Fundus fluorescein angiography of the bilateral retinal vessels revealed mottled hyperfluorescence and hypofluerescence and bilateral fundus autofluorescence associated with retinal pigment epithelium detachment consistent with VKH. ConclusionsVKH is a rare and potentially debilitating disorder in which severe complications can be avoided by early diagnosis and adequate treatment.Mainstay treatment includes corticosteroids and immunosuppressants.Viral infections such as cytomegalovirus (CMV) have been reported to trigger the development of VKH, possibly due to underlying molecular mimicry.COVID-19 was a potential immunological trigger of VKH in our patient, given infection onset was prior to the 2-week history of VKH onset.Although rare, COVID-19 may be considered a precipitant of VKH.

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Retinal Diseases and Treatments
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Bitemporal Hemianopia with Optic Chiasm Lesion: An Uncommon Presentation of MOGAD — Sushma Yerram, Paisith Piriyawat, et al. · Neurology (2024) | TGRS Research Map | TGRS