Antiglutamic Acid Decarboxylase 65 (GAD 65) Antibody-Associated Encephalitis Characterized with Choreo-dystonic Movements, Responsive to Steroid: A Case Report

conducted, using the I2 for statistical heterogeneity.GRADE criteria were used to identify the certainty of evidence. ResultsA total of 1598 studies were screened, and 13 studies were selected, representing a total of 358 patients with axonal GBS.All of them were observational studies.The pool proportion for clinical improvement at 4 weeks was 33% CI 95% [24%, 44%], and for achieving independent walking at 6 months was 75% CI 95% [60%, 85%].Only two studies reported IVIG vs Plasmapheresis showing a pooled OR of 3.59 CI 95% [0.71 , 18.02 ].Quality assessment showed a low-medium risk of bias. ConclusionsWith a low certainty, our findings suggest that IVIG could improve functional outcomes in patients with axonal GBS.There was no significant difference of efficacy between IVIG and plasmapheresis; however, larger randomized controlled trials are needed to confirm this finding.Study Supported By: N/A.