Deciphering farnesol’s anti-arthritic and immunomodulatory potential by targeting multiple pathways: a combination of network pharmacology guided exploration and experimental verification
The results pointed out the protective attributes of farnesol against formaldehyde and CFA-induced arthritis via modulation of multiple targets. This study provides a valuable reference for the development of a new treatment or complementary therapy for arthritis.
Authors
- Shaimaa R. Ahmed (ORCID: https://orcid.org/0000-0003-3336-4540)
- Omnia M. Hendawy
- Shah Jahan (ORCID: https://orcid.org/0000-0002-1730-5025)
- Hanan Khojah (ORCID: https://orcid.org/0000-0001-7901-5835)
- Ambreen Malik Uttra (ORCID: https://orcid.org/0000-0002-4800-4882)
- Muhammad Roman (ORCID: https://orcid.org/0000-0002-9035-2426)
- Eman K. Rashwan (ORCID: https://orcid.org/0000-0002-4100-8995)
- Sumera Qasim (ORCID: https://orcid.org/0000-0002-6082-6889)
- Muhammad Usman Minhas (ORCID: https://orcid.org/0000-0001-7313-8500)
Institutions
- University of Sargodha (PK)
- Jouf University (SA)
- University of Health Sciences Lahore (PK)
Publication Details
- Journal
- Journal of Pharmacy and Pharmacology
- Published
- 2024-10-07
- DOI
- https://doi.org/10.1093/jpp/rgae126
- Citations
- 4
- Primary Topic
- Computational Drug Discovery Methods
- Type
- article
- Field-Weighted Citation Impact
- 1.45