Integrated large-scale metagenome assembly and multi-kingdom network analyses identify sex differences in the human nasal microbiome
In summary, we construct the most comprehensive catalog of metagenome-assembled-genomes for the nasal bacterial community to provide a valuable resource for the understudied human nasal microbiome. On top of that, comparative analysis in relative abundance and microbial co-occurrence networks identify extensive sex differences in the respiratory tract community, which may help to further our understanding of the observed sex disparities in the respiratory diseases.
Authors
- Huanming Yang (ORCID: https://orcid.org/0000-0002-0858-3410)
- Ruijin Guo (ORCID: https://orcid.org/0000-0001-7863-3797)
- Shutian Lin
- Haorong Lu (ORCID: https://orcid.org/0000-0003-0132-8166)
- Kaiye Cai (ORCID: https://orcid.org/0000-0003-0593-1878)
- Qiang Sun (ORCID: https://orcid.org/0000-0002-6621-7064)
- Yanmei Ju (ORCID: https://orcid.org/0000-0002-1600-3164)
- Zewei Song (ORCID: https://orcid.org/0000-0002-0606-6946)
- Weiting Liang (ORCID: https://orcid.org/0000-0002-9573-5709)
- Huijue Jia (ORCID: https://orcid.org/0000-0002-3592-126X)
- Zhuye Jie (ORCID: https://orcid.org/0000-0003-0833-6134)
- Xin Tong (ORCID: https://orcid.org/0000-0002-4849-6522)
- Liang Xiao (ORCID: https://orcid.org/0000-0003-0312-7149)
- Xin Jin (ORCID: https://orcid.org/0000-0001-7554-4975)
- Jian Wang
- Zhe Zhang (ORCID: https://orcid.org/0000-0003-3983-1226)
- Xun Xu (ORCID: https://orcid.org/0000-0002-5338-5173)
- Mingliang Liu
- Wenwei Zhang (ORCID: https://orcid.org/0000-0001-9220-2467)
- Tao Zhang (ORCID: https://orcid.org/0000-0003-2765-2802)
- Peishan Chen (ORCID: https://orcid.org/0000-0002-6968-4303)
- Yong Hou (ORCID: https://orcid.org/0000-0002-1351-9288)
Institutions
- BGI Group (China) (CN)
- University of Toronto (CA)
- Fudan University (CN)
- Qingdao Academy of Agricultural Sciences (CN)
- Zhejiang Institute of Mechanical and Electrical Engineering (CN)
- China National GeneBank (CN)
- Precision Research (United States) (US)
- University of Chinese Academy of Sciences (CN)
- BGI Research (CN)
Publication Details
- Journal
- Genome biology
- Published
- 2024-10-08
- DOI
- https://doi.org/10.1186/s13059-024-03389-2
- Citations
- 11
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 2.57