Long-term outcome of Graves’ orbitopathy following treatment with sirolimus

Treatment with sirolimus is followed by a greater overall response of GO compared with methylprednisolone at 24 weeks, but not at 48 weeks, when only CAS is affected. A more prolonged period of treatment may be required for a better outcome to be observed over a longer period.

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Publication Details

Journal
Journal of Endocrinological Investigation
Published
2024-10-07
DOI
https://doi.org/10.1007/s40618-024-02470-8
Citations
12
Primary Topic
Ophthalmology and Eye Disorders
Type
article
Field-Weighted Citation Impact
5.10

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article

Long-term outcome of Graves’ orbitopathy following treatment with sirolimus

Michele Marinò, Maria Novella Maglionico, Giada Cosentino, Francesco Latrofa et al.
12 citations
Journal of Endocrinological Investigation
Ophthalmology and Eye Disorders
5.10
article

Long-term outcome of Graves’ orbitopathy following treatment with sirolimus

Michele Marinò, Maria Novella Maglionico, Giada Cosentino, Francesco Latrofa, Francesca Menconi, Ferruccio Santini, Giulia Lanzolla, Chiara Posarelli, Simone Comi, Michele Figus, Roberto Rocchi
article en
12 citations

Abstract

Treatment with sirolimus is followed by a greater overall response of GO compared with methylprednisolone at 24 weeks, but not at 48 weeks, when only CAS is affected. A more prolonged period of treatment may be required for a better outcome to be observed over a longer period.

Journal of Endocrinological InvestigationVol. 48(3)
University of Pisa (IT), Azienda Ospedaliera Universitaria Pisana (IT), University of Pennsylvania (US)
Università di Pisa
Good health and well-being
Openalex Percentile: Top 4%
Ophthalmology and Eye Disorders
5.10
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