Disulfiram ameliorates bone loss in ovariectomized mice by suppressing osteoclastogenesis
This study demonstrates that DSF could be a candidate for osteoporosis therapies because it suppresses osteoclastogenesis from an early stage in vivo.
Authors
- Masayuki Tsukasaki (ORCID: https://orcid.org/0000-0001-7278-9643)
- Hiroshi Takayanagi (ORCID: https://orcid.org/0000-0002-1462-4127)
- Yasunori Omata (ORCID: https://orcid.org/0000-0002-8912-7483)
- Taku Saito (ORCID: https://orcid.org/0000-0003-4911-3930)
- Etsuko Toda (ORCID: https://orcid.org/0000-0002-3091-8686)
- Sakae Tanaka (ORCID: https://orcid.org/0000-0001-9210-9414)
- Yuya Terashima (ORCID: https://orcid.org/0000-0003-3127-367X)
- Tadayoshi Hayata (ORCID: https://orcid.org/0000-0001-5083-4300)
- Kazuo Okamoto (ORCID: https://orcid.org/0000-0001-5855-5357)
- Asuka Terashima (ORCID: https://orcid.org/0000-0001-5150-5656)
- Ryota Chijimatsu (ORCID: https://orcid.org/0000-0002-3125-4818)
- Akiyoshi Saitoh (ORCID: https://orcid.org/0000-0002-7313-4902)
- Tatsuyuki Fukui
- Yukiko Fukuda (ORCID: https://orcid.org/0009-0000-4251-3275)
Institutions
- Kanazawa University (JP)
- Tokyo University of Science (JP)
- Okayama University Hospital (JP)
- University of Tokyo Hospital (JP)
- The University of Tokyo (JP)
- Nippon Medical School (JP)
Publication Details
- Journal
- Journal of Bone and Mineral Metabolism
- Published
- 2024-10-07
- DOI
- https://doi.org/10.1007/s00774-024-01555-x
- Citations
- 2
- Primary Topic
- Bone health and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.57
Funders
- University of Tokyo
- Japan Society for the Promotion of Science