Strengthening and expanding capacities in clinical trials: advancing pandemic prevention, preparedness and response in Africa
Enhancing the clinical trial capabilities within Africa is essential to augment the continent’s pandemic prevention, preparedness and response efforts. Here, we describe the critical challenges of clinical trials in Africa and draw upon the lessons learnt from the Consortium for COVID-19 Vaccine Clinical Trials (CONCVACT) experience, such as the importance of regional collaboration, capacity building and establishing standardized protocols.
Authors
- Michael Makanga (ORCID: https://orcid.org/0000-0003-0003-1520)
- Nebiyu Dereje (ORCID: https://orcid.org/0000-0001-5406-4171)
- Morẹ́nikẹ́ Oluwátóyìn Foláyan (ORCID: https://orcid.org/0000-0002-9008-7730)
- Jean Bisimwa Nachega (ORCID: https://orcid.org/0000-0002-2862-4443)
- Yap Boum (ORCID: https://orcid.org/0000-0002-6823-8539)
- Elvis Temfack (ORCID: https://orcid.org/0000-0001-8189-6555)
- Nicaise Ndembi (ORCID: https://orcid.org/0000-0001-5131-3136)
- Glaudina Loots
- Tajudeen Raji (ORCID: https://orcid.org/0000-0001-9849-5088)
- Samba O. Sow (ORCID: https://orcid.org/0000-0002-6335-5066)
- Francine Ntoumi (ORCID: https://orcid.org/0000-0003-4748-050X)
- Trevor A. Crowell (ORCID: https://orcid.org/0000-0001-5947-265X)
- Joseph Fokam (ORCID: https://orcid.org/0000-0002-1501-2763)
- Salim S. Abdool Karim (ORCID: https://orcid.org/0000-0002-4986-2133)
- Souleymane Mboup
- Ngashi Ngongo (ORCID: https://orcid.org/0000-0002-0460-937X)
- John Nkengasong
- Tadesse T. Mekonen
- A. Krüger
Institutions
- Henry M. Jackson Foundation (US)
- Stellenbosch University (ZA)
- Centre for the AIDS Programme of Research in South Africa (ZA)
- Department of Science,Technology and Innovation (ZA)
- Centre Pour le Développement des Vaccins-Mali (ML)
- Centre International De Reference Chantal Biya (CM)
- Institut Pasteur de Bangui (CF)
- Fondation Congolaise Pour La Recherche Médicale (CG)
- Africa Centres for Disease Control and Prevention (ET)
- President's Emergency Plan for AIDS Relief (US)
- Institute of Health Research, Epidemiological Surveillance and Training (SN)
- Joint Research Center (BE)
- Obafemi Awolowo University (NG)
- Columbia University (US)
- University of Tübingen (DE)
Publication Details
- Journal
- Nature Communications
- Published
- 2024-10-07
- DOI
- https://doi.org/10.1038/s41467-024-53126-3
- Citations
- 29
- Primary Topic
- Viral Infections and Outbreaks Research
- Type
- article
- Field-Weighted Citation Impact
- 11.28
Funders
- Henry M. Jackson Foundation
- Skoll Foundation
- Eberhard Karls Universität Tübingen
- Universiteit Stellenbosch
- Centers for Disease Control and Prevention
- Faculty of Medicine and Health, University of Sydney
- National Institute of Allergy and Infectious Diseases
- Mailman School of Public Health, Columbia University
- European and Developing Countries Clinical Trials Partnership