The RNA m5C methyltransferase NSUN1 modulates human malaria gene expression during intraerythrocytic development
<i>PfNSUN1</i> is a crucial RNA post-transcriptional modification protein in <i>P. falciparum</i>. It plays a pivotal role in regulating gene expression and parasite growth by targeting 28S ribosomal RNA and <i>pfap2-g5</i> transcription factor.
Authors
- Xinyu Cheng (ORCID: https://orcid.org/0000-0002-9637-1900)
- Qunfeng Jiang
- Ruoyu Tang (ORCID: https://orcid.org/0000-0001-9979-061X)
- Li Shen (ORCID: https://orcid.org/0000-0001-8427-9448)
- Zuping Zhang (ORCID: https://orcid.org/0000-0002-3295-2861)
- Binbin Lu (ORCID: https://orcid.org/0000-0001-9832-9995)
- Yanting Fan
- Xiaomin Shang
Institutions
- Tongji University (CN)
- Central South University (CN)
- Northwest University (CN)
- Shanghai East Hospital (CN)
- Tongji Hospital (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2024-10-07
- DOI
- https://doi.org/10.3389/fcimb.2024.1474229
- Citations
- 2
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.47
Funders
- Shanghai Municipal Health Commission
- National Natural Science Foundation of China
- Tongji University
- Natural Science Foundation of Hunan Province