Acute pancreatitis and biliary obstruction from metastatic lymph node compression during [177Lu] Lu-PSMA-617 therapy: a case report

Radioligand therapies such as [<sup>177</sup>Lu] Lu-PSMA-617 have gained significant momentum in cancer treatment after clinical trials and multicenter studies demonstrated their safety and efficacy. As these innovative treatments become more widespread, rare and unique clinical manifestations are expected to be observed. In this report, we describe a case with metastatic castration-resistant prostate cancer (mCRPC) and peripancreatic lymph node metastases who developed acute pancreatitis following [<sup>177</sup>Lu] Lu-PSMA-617 therapy.

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Publication Details

Journal
Frontiers in Oncology
Published
2024-10-07
DOI
https://doi.org/10.3389/fonc.2024.1442293
Citations
2
Primary Topic
Radiopharmaceutical Chemistry and Applications
Type
article
Field-Weighted Citation Impact
0.81
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article

Acute pancreatitis and biliary obstruction from metastatic lymph node compression during [177Lu] Lu-PSMA-617 therapy: a case report

Derek Richard Johnson, Oliver A. Sartor, Patrick J. Navin, A. Tuba Kendi et al.
2 citations
Frontiers in Oncology
Radiopharmaceutical Chemistry and Applications
0.81
article

Acute pancreatitis and biliary obstruction from metastatic lymph node compression during [177Lu] Lu-PSMA-617 therapy: a case report

Derek Richard Johnson, Oliver A. Sartor, Patrick J. Navin, A. Tuba Kendi, Gokce Belge Bilgin
article en
2 citations

Abstract

Radioligand therapies such as [<sup>177</sup>Lu] Lu-PSMA-617 have gained significant momentum in cancer treatment after clinical trials and multicenter studies demonstrated their safety and efficacy. As these innovative treatments become more widespread, rare and unique clinical manifestations are expected to be observed. In this report, we describe a case with metastatic castration-resistant prostate cancer (mCRPC) and peripancreatic lymph node metastases who developed acute pancreatitis following [<sup>177</sup>Lu] Lu-PSMA-617 therapy.

Frontiers in OncologyVol. 14
Mayo Clinic in Arizona (US)
Openalex Percentile: Top 25%
Radiopharmaceutical Chemistry and Applications
0.81
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Acute pancreatitis and biliary obstruction from metastatic lymph node compression during [177Lu] Lu-PSMA-617 therapy: a case report — Derek Richard Johnson, Oliver A. Sartor, et al. · Frontiers in Oncology (2024) | TGRS Research Map | TGRS