A rare case of early-onset neonatal sepsis caused by Proteus mirabilis in the first infant of tetrachorionic triamniotic triplets

Early-onset neonatal sepsis (EОNS) is one of the most severe diseases of the neonatal period and is often coupled to extremely unfavorable outcomes. In many ways, the severity of the condition and the results of newborn nursing depend on the etiology of the bacterial process. The major EОNS pathogens are traditionally considered to be Streptococcus group B and E. coli , much less common are other Gram-negative bacteria including casuistic cases caused by caused by Proteus mirabilis ( P. mirabilis ). The article provides a review on the P. mirabilis role in developing neonatal sepsis with pathogen-specific disease course and outcomes. In addition, we describe a clinical case of P. mirabilis -caused EОNS not only primarily characterized by the rarity of its causative agent, but also that it proceeded with a more favorable brain damage in contrast to similar cases described worldwide and because the neonatal EОNS developed in one of triplets, with two other babies being asymptomatic despite that P. mirabilis was also detected.

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Publication Details

Journal
Obstetrics Gynecology and Reproduction
Published
2024-10-07
DOI
https://doi.org/10.17749/2313-7347/ob.gyn.rep.2024.543
Citations
1
Primary Topic
Neonatal and Maternal Infections
Type
article
Field-Weighted Citation Impact
0.54
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article

A rare case of early-onset neonatal sepsis caused by Proteus mirabilis in the first infant of tetrachorionic triamniotic triplets

E. А. Dudkina, N.Yu. Karpov, А. В. Мостовой, Orlova Oe et al.
1 citations
Obstetrics Gynecology and Reproduction
Neonatal and Maternal Infections
0.54
article

A rare case of early-onset neonatal sepsis caused by Proteus mirabilis in the first infant of tetrachorionic triamniotic triplets

E. А. Dudkina, N.Yu. Karpov, А. В. Мостовой, Orlova Oe, O. V. Avdei, А.Л. Карпова, L. A. Anikeeva, A. P. Khoteeva, S. P. Zagdai
article en
1 citations

Abstract

Early-onset neonatal sepsis (EОNS) is one of the most severe diseases of the neonatal period and is often coupled to extremely unfavorable outcomes. In many ways, the severity of the condition and the results of newborn nursing depend on the etiology of the bacterial process. The major EОNS pathogens are traditionally considered to be Streptococcus group B and E. coli , much less common are other Gram-negative bacteria including casuistic cases caused by caused by Proteus mirabilis ( P. mirabilis ). The article provides a review on the P. mirabilis role in developing neonatal sepsis with pathogen-specific disease course and outcomes. In addition, we describe a clinical case of P. mirabilis -caused EОNS not only primarily characterized by the rarity of its causative agent, but also that it proceeded with a more favorable brain damage in contrast to similar cases described worldwide and because the neonatal EОNS developed in one of triplets, with two other babies being asymptomatic despite that P. mirabilis was also detected.

Obstetrics Gynecology and ReproductionVol. 18(5)
Lomonosov Moscow State University (RU), Yaroslavl State Medical Academy (RU), Russian Medical Academy of Continuous Professional Education (RU), City Clinical Hospital (RU), Moscow State University (TJ), York District Hospital (US)
Openalex Percentile: Top 28%
Neonatal and Maternal Infections
0.54
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