Neuroprotective Effects of Astragalus Polysaccharide on Retina Cells and Ganglion Cell Projection in NMDA-Induced Retinal Injury
Our findings reveal that APS shields the retina from NMDA-induced damage by inhibiting the NF-κB signaling pathway and reduces the detrimental effects of NMDA on RGC projections to the visual centers. These findings propose APS as a potential novel therapeutic agent for the treatment of retinal diseases.
Authors
- Baige Li
- Zeyuan Pu
- Gao Tan (ORCID: https://orcid.org/0000-0002-6959-2249)
- Yin Shen
- Tianlu Zhang
Institutions
- Wuhan University (CN)
- Frontier Science Foundation (CH)
- Eye Center (SA)
- Renmin Hospital of Wuhan University (CN)
Publication Details
- Journal
- Current Eye Research
- Published
- 2024-10-07
- DOI
- https://doi.org/10.1080/02713683.2024.2412304
- Citations
- 1
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.54
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China