A reductive amination approach for the synthesis of catalytic peptide foldamers
first crystallographic characterization of an imino surrogate for a peptide bond between two amino acids; -turn conformation stabilized by an intramolecular N-HO=C hydrogen bond; reduction of the imino group allows the formation of the [CH 2 NH] moiety. = vs = vsCurrently being tested.. Reductive amination cappingBifunctional catalytic site Chiral initiator/controller
Authors
- Matteo Pollastrini (ORCID: https://orcid.org/0000-0001-9334-2613)
- Alessandro Moretto (ORCID: https://orcid.org/0000-0003-1563-9053)
Publication Details
- Published
- 2024-09-20
- DOI
- https://doi.org/10.17952/37eps.2024.p2255
- Primary Topic
- Chemical Synthesis and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00