Peptides Conjugated to Sugars as Therapeutics for Ebola & Cancer disease
Mucin 1 or (MUC1) is a membrane-associated protein highly O-glycosylated through Ser/Thr residues.This protein is highly glycosylated in healthy cells, whereas in tumour cells it carries simple and truncated carbohydrates and exposes fragments, such as APDTRP or Tn antigen [Thr/Ser(-GalNAc)], which can trigger the production of anti-MUC1 antibodies.Vaccines incorporating these structures are a promising field of research (Asn et al.
Authors
- Jesús Manuel Peregrina (ORCID: https://orcid.org/0000-0003-3778-7065)
- Ana Gimeno (ORCID: https://orcid.org/0000-0001-9668-2605)
- Asuka Nanbo (ORCID: https://orcid.org/0000-0001-8764-1350)
- Elena Lalinde (ORCID: https://orcid.org/0000-0001-7402-1742)
- Jesús R. Berenguer (ORCID: https://orcid.org/0000-0002-6539-7171)
- Gonzalo Millán (ORCID: https://orcid.org/0000-0001-8151-7551)
- Jesús Jiménez‐Barbero (ORCID: https://orcid.org/0000-0001-5421-8513)
- Filipa Marcelo (ORCID: https://orcid.org/0000-0001-5049-8511)
- Fayna García‐Martin (ORCID: https://orcid.org/0000-0001-9118-3874)
- Francisco Corzana (ORCID: https://orcid.org/0000-0001-5597-8127)
- Juan Anguíta (ORCID: https://orcid.org/0000-0003-2061-7182)
- Héctor Busto
Publication Details
- Published
- 2024-09-20
- DOI
- https://doi.org/10.17952/37eps.2024.p2216
- Primary Topic
- Influenza Virus Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00