Comprehensive analysis identifies YKT6 as a potential prognostic and diagnostic biomarker in lung adenocarcinoma

Elevated YKT6 expression is related to poor prognosis of LUAD patients. YKT6 can serve as a novel biomarker for LUAD diagnosis and prognosis. Cell proliferation, migration and invasion was impaired with increased apoptosis upon YKT6 silencing in lung cancer cells. In summary, this study comprehensively uncovered that YKT6 could be identified as a potential prognostic and diagnostic biomarker in LUAD.

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Publication Details

Journal
BMC Cancer
Published
2024-10-07
DOI
https://doi.org/10.1186/s12885-024-12975-3
Citations
10
Primary Topic
RNA modifications and cancer
Type
article
Field-Weighted Citation Impact
2.34

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article

Comprehensive analysis identifies YKT6 as a potential prognostic and diagnostic biomarker in lung adenocarcinoma

Lina Wang, Liming Zhang, Shaoqiang Wang
10 citations
BMC Cancer
RNA modifications and cancer
2.34
article

Comprehensive analysis identifies YKT6 as a potential prognostic and diagnostic biomarker in lung adenocarcinoma

Lina Wang, Liming Zhang, Shaoqiang Wang
article en
10 citations

Abstract

Elevated YKT6 expression is related to poor prognosis of LUAD patients. YKT6 can serve as a novel biomarker for LUAD diagnosis and prognosis. Cell proliferation, migration and invasion was impaired with increased apoptosis upon YKT6 silencing in lung cancer cells. In summary, this study comprehensively uncovered that YKT6 could be identified as a potential prognostic and diagnostic biomarker in LUAD.

BMC CancerVol. 24(1)
Weifang People's Hospital (CN), Affiliated Hospital of Jining Medical University (CN)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 11%
RNA modifications and cancer
2.34
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