Causality between Telomere Length and the Risk of Hematologic Malignancies: A Bidirectional Mendelian Randomization Study
In contrast to observational studies, this study uncovered the reliable causal relationships between TL and hematologic malignancies, emphasizing the potential role of telomeres in tumor development. TL maintenance may offer a promising strategy to reduce the risk of hematologic malignancies.
Authors
- Yunshan Wang (ORCID: https://orcid.org/0000-0001-5234-8752)
- Guoyun Jiang
- LingXiao Cao (ORCID: https://orcid.org/0000-0003-1786-7455)
- Bin Feng
- Hui Zhao
- Li Li (ORCID: https://orcid.org/0000-0002-5701-8354)
- Zie Wang
- Yang Qiu
Institutions
- Second Hospital of Shandong University (CN)
- Shandong Provincial Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Cancer Research Communications
- Published
- 2024-10-01
- DOI
- https://doi.org/10.1158/2767-9764.crc-24-0402
- Citations
- 1
- Primary Topic
- Telomeres, Telomerase, and Senescence
- Type
- article
- Field-Weighted Citation Impact
- 0.33
Funders
- Natural Science Foundation of Shandong Province