Determination of MYD88 and CXCR4 Mutations for Clinical Detection and Their Significance in Waldenström Macroglobulinemia
Testing for MYD88 mutations using AS-PCR or ddPCR in unsorted samples is viable for routine clinical practice. Under BTKi treatment, MYD88 and CXCR4 mutations hold greater prognostic importance than IPSSWM staging in WM.
Authors
- Wenjie Xiong (ORCID: https://orcid.org/0000-0002-0302-0408)
- Zhijian Xiao (ORCID: https://orcid.org/0000-0001-8008-7385)
- Yuxi Li (ORCID: https://orcid.org/0009-0005-1112-9656)
- Dehui Zou (ORCID: https://orcid.org/0000-0002-8135-4913)
- Lugui Qiu (ORCID: https://orcid.org/0000-0002-8752-0644)
- Gang An (ORCID: https://orcid.org/0000-0003-4922-4614)
- Shuhua Yi (ORCID: https://orcid.org/0000-0002-6291-812X)
- Hao Sun (ORCID: https://orcid.org/0000-0002-9081-0116)
- Yao Yao (ORCID: https://orcid.org/0000-0002-4224-1369)
- Mu Hao (ORCID: https://orcid.org/0000-0001-8621-4840)
- Tingyu Wang (ORCID: https://orcid.org/0000-0003-4542-3587)
- Yuting Yan (ORCID: https://orcid.org/0000-0002-9355-2984)
- Haoxu Wang (ORCID: https://orcid.org/0009-0001-7876-3417)
- Weiwei Sui (ORCID: https://orcid.org/0000-0002-6982-8258)
- Jianxiang Wang (ORCID: https://orcid.org/0000-0001-9437-9151)
- Yan Xu (ORCID: https://orcid.org/0000-0002-6167-3319)
- Wei Liu (ORCID: https://orcid.org/0000-0002-0448-7210)
- Jun Wang (ORCID: https://orcid.org/0000-0002-1516-7781)
- Ying Yu (ORCID: https://orcid.org/0000-0001-7362-2925)
- Zhen Yu (ORCID: https://orcid.org/0009-0003-3169-077X)
- Yanshan Huang (ORCID: https://orcid.org/0009-0002-4833-1223)
- Rui Lv
- Yujiao Jia (ORCID: https://orcid.org/0009-0000-5751-9151)
- Wang Qi (ORCID: https://orcid.org/0009-0006-1763-1089)
- Wenyang Huang
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- Tianjin Medical University Cancer Institute and Hospital (CN)
- Institute of Hematology & Blood Diseases Hospital (CN)
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2024-10-07
- DOI
- https://doi.org/10.1158/1078-0432.ccr-23-3939
- Citations
- 8
- Primary Topic
- Chronic Lymphocytic Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 3.50
Funders
- National Natural Science Foundation of China
- Chinese Academy of Medical Sciences
- Chinese Academy of Medical Sciences Initiative for Innovative Medicine